We revolutionize the way diseases are analyzed, detected, and managed
CRISPR detection of infectious diseases
Infectious diseases, such as SARS-CoV-2 and the Influenza virus, pose a serious global health risk because they can spread quickly. Our team is working on a new diagnostic method that can simultaneously test for multiple viruses. We're using innovative CRISPR technology, a cutting-edge multiplexed detection system, and a portable detector to create a fast and accurate diagnostic tool that can be used in the field. Our approach addresses the limitations of current lab-based tests and has the potential to greatly improve global health monitoring and management of infectious diseases.
Imaging disease-causing cell-cell interactions
The diversity of cell types, their arrangement in space, and the interactions between them play critical roles in the progression of cancer and neurodegenerative diseases. We aim to unravel those complexities through advanced live-imaging methods and novel cell modification techniques. By visually interrogating cell-cell interactions that are enriched in diseases, such as those between immune and cancer cells, we seek to gain a deeper understanding of disease mechanisms and facilitate the design of personalized medicine.
Developing technologies for single molecule and cell analysis
We are interested in the characterization of molecular and cellular properties through individual-level analysis. This approach provides a deep understanding of the inherent heterogeneity present within targets such as cancer cells and host cells infected with a virus. Utilizing cutting-edge Micro-Electro-Mechanical Systems (MEMS) technologies, microfluidic droplets, and barcoding strategies, we aim to facilitate individual-level analysis of molecules and cells with a particular emphasis on gathering a quantitative and physical information in high-throughput.