Recruiting 2025 interns to develop experimental methods for AI-driven protein engineering

Project Scope

• Engineer Cas13a variants to advance point-of-care CRISPR diagnostics.

• Develop and optimize iterative cloning and purification pipelines for protein variants, guided by structural insights.

• Integrate state-of-the-art AI prediction tools to accelerate protein engineering efficiency.

References

• Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy, Cell (2021)

• The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a, Cell (2017)

• Rapid in silico directed evolution by a protein language model with EVOLVEpro, Science (2024)

Inquiries: email smson@kaist.ac.kr